At Otsuka, our research is driven by a commitment to improving the lives of people living with serious and complex diseases. As part of Otsuka’s global research and development network, we work to advance innovative medicines that address unmet medical needs and contribute to better health outcomes.
We continue to step-up to the challenges in therapeutic areas where we believe research has the greatest potential to make a meaningful difference.
By leveraging our expertise and taking a patient-centred approach, we explore new ways to address complex diseases and contribute to the future of healthcare.
Neuroscience
Mental and neurological disorders are among the leading causes of disability worldwide, affecting millions of people, their families and carers. Advancing our understanding of the brain is essential to developing new approaches that improve treatment and quality of life.
Otsuka has a proud history and long-standing commitment to neuroscience research, exploring the biological pathways that influence psychiatric and neurological disorders. Our groundbreaking research spans serious mental illnesses such as schizophrenia as well as neurodegenerative diseases, with a focus on developing innovative therapies that address complex patient needs.
By combining scientific discovery with clinical research and collaboration, we aim to improve outcomes and help people live healthier, more independent lives.
Nephrology & Immunology
Kidney disease and immune-mediated disorders can have a significant impact on long-term health, making earlier diagnosis and innovative treatments critical to improving patient outcomes. Otsuka’s research in nephrology and immunology is focused on deepening our understanding of the underlying biological mechanisms that drive disease and on developing therapies that address unmet patient needs.
Our global research efforts include advancing treatments for chronic and inherited kidney diseases, such as autosomal dominant polycystic kidney disease (ADPKD) and IgA Nephropathy (IgAN), while also exploring therapies for autoimmune and other immune-mediated conditions. By applying advances in molecular biology, precision medicine, and clinical science, Otsuka is working to develop targeted treatments that address disease pathways and support improved long-term management. Through ongoing research and clinical collaborations, we remain committed to driving innovation that helps people live better with kidney and immune-related diseases.
Rare Diseases
Although each rare disease affects a relatively small number of people, collectively they impact millions worldwide. Many patients experience delayed diagnosis, limited treatment options and significant challenges throughout their healthcare journey.
Otsuka is committed to advancing research in rare diseases where there is a high unmet medical need. For example, we have established clinical development programs in phenylketonuria (PKU), a rare inherited metabolic disorder; hereditary angioedema (HAE), a rare genetic disorder characterised by recurrent attacks of swelling; and FUS-associated amyotrophic lateral sclerosis (FUS-ALS), a rare genetic form of ALS affecting motor neurons.
Our goal is to help create a future where people living with rare diseases have access to earlier diagnosis, more effective, affordable treatment options and better quality of life.